Upper and lower respiratory infections, including
pharyngitis, bronchitis, and pneumonia, are
exceedingly common and the cause of significant
morbidity and mortality around the world.
Pneumonia, especially, is a known killer. Pneumonia
is the most deadly infectious disease in the US,
causing on the order of 100,000 deaths annually. It
is the 6th leading cause of death in that country.
Approximately 5.1 million cases are reported each
Causes of pneumonia in adults include not only S.
pneumonia and H.influenzae but also Legionella,
which is a leading cause of both community-acquired
and hospital-acquired pneumonia. There are 25,000
to 100,000 cases of Legionnairesí Disease reported
in the US annually, and this is one of the most
overlooked causes of pneumonia. The mortality rate
associated with Legionnairesí Disease is 25% to 40%,
so the need to detect Legionella quickly is high.